I use this blog myself as my own personal reference for fixes to annoying problems. One such issue is being unable to install a Microsoft-signed ClickOnce application.
If you get the following error,
Your security settings do not allow this application to be installed on your computer.
Run this command in Powershell as an Administrator.
Set-Itemproperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'Internet' -value 'Enabled'
Set-Itemproperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'LocalIntranet' -value 'Enabled'
Set-Itemproperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'MyComputer' -value 'Enabled'
Set-Itemproperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'TrustedSites' -value 'Enabled'
Set-Itemproperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'UntrustedSites' -value 'Enabled'
If that doesn’t work try this,
New-Item "HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel" -force | Out-Null
New-ItemProperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'Internet' -value 'Enabled'
New-ItemProperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'LocalIntranet' -value 'Enabled'
New-ItemProperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'MyComputer' -value 'Enabled'
New-ItemProperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'TrustedSites' -value 'Enabled'
New-ItemProperty -path 'HKLM:\SOFTWARE\MICROSOFT\.NETFramework\Security\TrustManager\PromptingLevel' -Name 'UntrustedSites' -value 'Enabled'
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